1422540-39-3

Basic information

• Product Name: 2,6-difluoro-N-(3-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamido)benzamide
• Synonyms: 2,6-difluoro-N-(3-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamido)benzamide
• CAS NO: 1422540-39-3
• Molecular Weight: 411.389
• Mol File: 1422540-39-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-difluoro-N-(3-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamido)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-difluoro-N-(3-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamido)benzamide(1422540-39-3)
• EPA Substance Registry System: 2,6-difluoro-N-(3-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamido)benzamide(1422540-39-3)

Safety Data

• Hazardous Substances Data: 1422540-39-3(Hazardous Substances Data)

Upstream product

• 1186193-95-2 methyl 2,6-difluoro-3-(N-(propylsulfonyl)propylsulfonamido)benzoate 
• 84832-02-0 methyl 3-amino-2,6-difluorobenzoate 
• 84832-01-9 methyl 2,6-difluoro-3-nitrobenzoate 
• 13671-00-6 methyl 2,6-difluorobenzoate 
• 385-00-2 2,6-difluorobenzoic acid 
• 1186607-05-5 Raf inhibitor a 
• 1186614-21-0 3-methoxy-5-nitro-1H-pyrazolo[3,4-b]pyridine 

Downstream Products

• 1422540-40-6 2,6-difluoro-N-(3-[¹¹C]methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide 

Relevant articles and documents

Synthesis of 2,6-difluoro-N-(3-[11C]methoxy-1H-pyrazolo[3,4-b] pyridine-5-yl)-3-(propylsulfonamidio)benzamide as a new potential PET agent for imaging of B-RafV600E in cancers

The authentic standard 2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b] pyridine-5-yl)-3-(propylsulfonamidio)benzamide was synthesized from 2,6-difluorobenzoic acid and 3-amino-5-hydroxypyrazole in 9 steps with 1% overall chemical yield. Direct desmethylation