142272-83-1Relevant academic research and scientific papers
Asymmetric Synthesis of Axially Chiral 2-Aminobiaryls by Rhodium-Catalyzed Benzannulation of 1-Arylalkynes with 2-(Cyanomethyl)phenylboronates
Xue, Fei,Hayashi, Tamio
supporting information, p. 10368 - 10372 (2018/07/31)
Asymmetric benzannulation of 1-arylalkynes, where the aryl group is an ortho-substituted aromatic group, with 2-(cyanomethyl)phenylboronate was catalyzed by a rhodium complex coordinated with a chiral diene ligand to give high yields of axially chiral 2-aminobiaryls with greater than 90 % ee.
A flexible synthesis of indoline, indolizidine, and pyrrolizidine derivatives
Bytschkov, Igor,Siebeneicher, Holger,Doye, Sven
, p. 2888 - 2902 (2007/10/03)
New and flexible procedures for the synthesis of indoline, indolizidine, and pyrrolizidine derivatives are described. By these new procedures, the target compounds can be synthesized with high diversity from three building blocks (ortho-bromo- or ortho-ch
Alkoxyacetylenes from alkyl 1,2-dichlorovinyl ethers
Loffler,Himbert
, p. 495 - 498 (2007/10/02)
Alkyl 1,2-dichlorovinyl ethers 4, prepared from sodium alkoxides 1 and trichloroethylene 2, react in tetrahydrofuran with two equivalents of butyllithium to afford lithium alkoxyacetylides 5. On the one hand, these acetylides react with ketones or dichlor
Ethynylbenzene compounds and derivatives thereof in the treatment of pain, fever or inflammation
-
, (2008/06/13)
A method of treating inflammation, pain or fever in a warm blooded animal by administering an effective amount of a compound which is a cyano ethynylbenzene, and the pharmaceutical preparation thereof.
Ethynylbenzene compounds and derivatives thereof
-
, (2008/06/13)
Novel ethynylbenzene compounds and derivatives are described. Their use in the treatment of inflammation is also disclosed.
