1422721-78-5

Basic information

• Product Name: C₁₈H₁₇NO₂
• Synonyms: C₁₈H₁₇NO₂
• CAS NO: 1422721-78-5
• Molecular Weight: 279.338
• Mol File: 1422721-78-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₇NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₇NO₂(1422721-78-5)
• EPA Substance Registry System: C₁₈H₁₇NO₂(1422721-78-5)

Safety Data

• Hazardous Substances Data: 1422721-78-5(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 2621-78-5 ethyl N-benzylcarbamate 
• 932-87-6 1-Bromo-2-phenylacetylene 

Downstream Products

• 1422721-67-2 (E)-ethyl benzyl(1-iodo-2-phenylvinyl)carbamate 
• 1422721-68-3 (E)-ethyl benzyl(1-bromo-2-phenylvinyl)carbamate 

Relevant articles and documents

Stereoselective Synthesis of Pyrido- and Pyrrolo[1,2-c][1,3]oxazin-1-ones via a Nucleophilic Addition-Cyclization Process of N,O-Acetal with Ynamides

An efficient asymmetric approach to access functionalized pyrido- and pyrrolo[1,2-c][1,3]oxazin-1-ones has been developed through a nucleophilic addition-cyclization process of N,O-acetal with ynamides. A number of substituted ynamides 8a-8o and 3-silyloxypyrrolidine or piperidine N,O-acetals 6a, 7 were amenable to this transformation, and the desired products 9a-9o, 10a-10m were obtained with excellent regioselectivities and outstanding diastereoselectivities. Moreover, chiral ynamides 14a-14f could also experience this addition-cyclization process to afford products 15a-15f in excellent yields.

Regio- and stereospecific synthesis of (E)-α-iodoenamide moieties from ynamides through iodotrimethylsilane-mediated hydroiodation

A facile approach to (E)-α-haloenamide moieties from ynamides using bromo- or iodotrimethylsilane is described. The simple protocol enables a regio- and stereospecific hydrohalogenation of the triple bond in gram-scale and provides a general entry for synthesis of novel enamide analogues.