142273-34-5

Upstream product

• 1877-73-2 3-nitro-benzeneacetic acid 
• 5247-25-6 2-(3-nitrophenyl)acetic acid amide 

Downstream Products

• 1318758-17-6 ethyl 4-methyl-2-(3-nitrobenzyl)-1,3-thiazole-5-carboxylate 
• 1318757-06-0 1-methyl-N-[4-methyl-2-(3-nitrobenzyl)-1,3-thiazol-5-yl]-1H-pyrazole-5-carboxamide 
• 1318758-18-7 4-methyl-2-(3-nitrobenzyl)-1,3-thiazole-5-carboxylic acid 
• 1318758-19-8 tert-butyl [4-methyl-2-(3-nitrobenzyl)-1,3-thiazol-5-yl]carbamate 

Relevant academic research and scientific papers

ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF

The invention provides anti-VISTA antibody drug conjugates which may be used for targeted delivery of anti-inflammatory agents such as steroids to immune cells, e.g., myeloid cells. The invention also provides methods of using anti-VISTA antibody drug conjugates in the treatment of inflammatory and/or autoimmune conditions and/or for alleviating the toxicity of anti-inflammatory agents such as steroids.