142287-15-8

Basic information

• Product Name: 2-(nonyloxy)ethanol
• Synonyms: Ethanol, 2-(nonyloxy)-; Poly(oxy-1,2-ethanediyl), alpha-nonyl-omega-hydroxy-
• CAS NO: 142287-15-8
• Molecular Formula: C₁₁H₂₄O₂
• Molecular Weight: 188.3071
• Mol File: 142287-15-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 258.6°C at 760 mmHg
• Flash Point: 68.3°C
• Density: 0.88g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.439
• CAS DataBase Reference: 2-(nonyloxy)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(nonyloxy)ethanol(142287-15-8)
• EPA Substance Registry System: 2-(nonyloxy)ethanol(142287-15-8)

Safety Data

• Hazardous Substances Data: 142287-15-8(Hazardous Substances Data)

Upstream product

• 75-21-8 oxirane 
• 143-08-8 nonyl alcohol 
• 693-58-3 1-Bromononane 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 4536-30-5 ethylene glycol mono-n-dodecyl ether 
• 107-21-1 ethylene glycol 
• 143-15-7 1-dodecylbromide 
• 5432-30-4 2-octyl-1,3-dioxolane 
• 112-42-5 undecyl alcohol 
• 1188-97-2 triundecylborane 

Relevant articles and documents

Guests of differing polarities provide insight into structural requirements for templates of water-soluble nano-capsules

Guests covering a range of polarities were examined for their ability to bind to a water-soluble cavitand and trigger its assembly into a supramolecular capsule. Specifically the guests examined were: tridecane 2, 1-dodecanol 3, 2-nonyloxy ethanol (ethylene glycol monononyl ether) 4, 2-(2-hexyloxyethoxy) ethanol (di(ethylene glycol) hexyl ether) 5, 2-[2-(2 propoxyethoxy)ethoxy] ethanol (tri(ethylene glycol) propyl ether) 6, and bis [2-(2-hydroxyethoxy)ethyl] ether (tetra(ethylene glycol)) 7. In this series, guest 6 proved to signify the boundary between assembly and the formation of 2:1 complexes, and simple 1:1 complexation. Thus, guests 2-5 formed relatively kinetically stable capsules, guest 6 formed a capsule that was unstable relative to the NMR timescale, and guest 7 formed a simple 1:1 complex.

Fosaprepitant derivative, synthesis thereof, and use thereof in long acting preparation

The invention relates to a Fosaprepitant derivative, a synthesis thereof, and a use thereof in a long acting preparation. The invention relates to a compound of formula (I), and a salt, an N-oxide, a quaternary ammonium and a stereoisomer thereof. R to R in the formula (I) are as defined in claims. The invention also relates to an intermediate for preparing the compound of formula (I), and a method for preparing the compound of formula (I). The invention further relates to a use of the compound of formula (I) as a drug especially used for preventing chemotherapy induced acute and late nausea and vomiting.

Synthesis of some acyclic quaternary ammonium compounds. Alkylation of secondary and tertiary amines in a two-phase system

A series of acyclic symmetrical and asymmetrical quaternary ammonium chlorides of the general formula R1R2R3N+AR4Cl- (R1 = Me, Bu; R2 = n-C12H25, PhCH2, C n H2n+1(OCH2CH2) m, n = 9 and 12, m = 1 and 2; R3 = n-C12H25, PhCH2, HOCH2CH2,-OOCCH2; R4 = n-C12H25, PhCH2; A = (CH2CH2O)1,2, CH2C(O)O) was synthesized by the alkylation of tertiary amines in a two-phase system containing water. A convenient method for the synthesis of the initial symmetrical and asymmetrical tertiary amines of the general formula MeNR1R2 (R1 = Me, Bu; R2 = n-C12H25, PhCH2, CnH2n+1(OCH2CH2) m, n = 9 and 12, m = 1 and 2) in an organic phase-aqueous phase heterogeneous system, which allows the use of aqueous solutions of alkali and amines, was developed. The improved method for the preparation of intermediate ethylene glycol and diethylene glycol monoethers is monoalkylation of glycols in dioxane using solid KOH in a two-phase system.