1422968-29-3Relevant academic research and scientific papers
Benzosultines as sulfur dioxide (SO2) donors
Malwal, Satish R.,Gudem, Mahesh,Hazra, Anirban,Chakrapani, Harinath
, p. 1116 - 1119 (2013/04/23)
In order to understand precise biological roles of sulfur dioxide (SO 2), reliable SO2 donors, compounds that produce SO 2 under physiological conditions, are necessary. The design and development of 1-phenyl-benzosultine as an efficient SO2 donor is reported. This compound undergoes cycloreversion to generate SO2 upon dissolution in aqueous buffer at 37 C with a yield of 89% and a half-life of 39 min and shows SO2-like biological activity in a DNA cleavage assay.
