1423018-75-0Relevant academic research and scientific papers
Stereoselective preparation of chiral compounds in Mannich-type reactions of a bicyclic imine and phenols or indole Dedicated to Professor Jacek Skarzewski on the occasion of his 65th birthday
Iwanejko, Jakub,Wojaczyńska, Elzbieta,Wojaczyński, Jacek,B?kowicz, Julia
, p. 6619 - 6622 (2015/02/18)
Mannich-type reactions of a chiral bicyclic imine and various nucleophiles yield the corresponding adducts with good to high diastereoselectivity. The influence of the reaction conditions on the yield and stereochemical outcome is investigated. The configuration of the products is established by 1H NMR spectroscopy, and the major isomers of two adducts are characterized by X-ray crystallography.
Monoimine derived from trans-1,2-diaminocyclohexane and ethyl glyoxylate: An intermediate in aza-Diels-Alder and Mannich reactions
Wojaczynska, Elzibieta,Baikowicz, Julia,Dorsz, Mateusz,Skarziewski, Jacek
, p. 2808 - 2811 (2013/04/23)
Novel enantiopure policyclic nitrogen heterocycles have been obtained in the diastereoselective aza-Diels-Alder or Mannich reaction of dienes with imine formed in situ from ethyl glyoxylate and (1R,2R)-diaminocyclohexane.
