1423046-39-2

Upstream product

• 1423046-31-4 (S)-9-(tert-butyldimethylsilyloxy)-4-isopropyl-9-hydroxy-7,7-(ethan-1,2-diyl)-2',3',5',6,6',7,8,9-octahydro-3H-spiro[furo[3,4-c]quinoline-1,4'-pyran]-3-one 
• 62266-37-9 cyclopropylidenepropanone 
• 1423046-34-7 (9S)-9-(tert-butyldimethylsilyloxy)-4-isopropyl-9-hydroxy-7,7-(ethan-1,2-diyl)-3-(4-(trifluoromethyl)phenyl)-2′,3′,5′,6,6′,7,8,9-octahydro-3H-spiro[furo[3,4-c]quinoline-1,4′-pyran]-3-ol 
• 1423046-33-6 (S)-4-isopropyl-9-hydroxy-,7,7-(ethan-1,2-diyl)-2',3',5',6,6',7,8,9-octahydro-3H-spiro[furo[3,4-c]quinoline-1,4'-pyran]-3-one 
• 1423046-32-5 4-isopropyl-7,7-(ethan-1,2-diyl)-2',3',5',6',7,8-hexahydro-3H-spiro[furo[3,4-c]quinoline-1,4'-pyran]-3,9(6H)-dione 
• 1332491-62-9 3-isobutyryl-1,8-dioxaspiro[4.5]dec-3-en-2-one 
• 42558-54-3 Methyl 4-methyl-3-oxopentanoate 
• 1332491-60-7 3-isobutyryl-1,8-dioxaspiro[4.5]decan-2-one 
• 1373388-85-2 7-amino-spiro[2.5]oct-6-en-5-one 
• 1423046-30-3 7-hydroxyspiro[2.5]oct-6-en-5-one 

Relevant academic research and scientific papers

Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation

The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol es

FURO[3,4-C]QUINOLINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION

The present invention relates to compounds defined by formula (I), wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol