142362-78-5Relevant articles and documents
Inter- and Intramolecular Hetero Diels-Alder Reactions, 41. - Unusual Stereocontrol in Intramolecular Hetero Diels-Alder Reactions of 2-Aza-1,3-butadienes. A Stereoselective Sequential Synthesis of Annulated Tetrahydropyridines
Tietze, Lutz F.,Utecht, Jens
, p. 2259 - 2264 (2007/10/02)
Condensation of aldehydes 1a-e with 5-amino-3-methylisoxazole (4) gives the corresponding imines 5a-e with a 2-aza-1,3-butadiene moiety, which cyclize selectively, e.g. 5a to form the trans-fused tetrahydropyridine 7a and 5c to yield the cis-fused cycload