142362-83-2Relevant academic research and scientific papers
Synthesis of 1-Substituted 1,2,3,4-Tetrahydroisoquinolines from Enamino Ketones
Tietze, Lutz F.,Schimpf, Ralph,Wichmann, Juergen
, p. 2571 - 2576 (2007/10/02)
The reaction of the N-acylated enamino ketones 4a-d with trifluoroacetic acid, TMS triflate, or Lewis acids leads to the 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines 5a-d in 84 to 94percent yield.The enamino ketones 4f-i can only be cyclized with trifluo
