142363-65-3

Basic information

• Product Name: 1-(2-chlorophenyl)-2-(n-propylamino)ethanol
• Synonyms: 1-(2-chlorophenyl)-2-(n-propylamino)ethanol
• CAS NO: 142363-65-3
• Molecular Weight: 213.707
• Mol File: 142363-65-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-chlorophenyl)-2-(n-propylamino)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chlorophenyl)-2-(n-propylamino)ethanol(142363-65-3)
• EPA Substance Registry System: 1-(2-chlorophenyl)-2-(n-propylamino)ethanol(142363-65-3)

Safety Data

• Hazardous Substances Data: 142363-65-3(Hazardous Substances Data)

Upstream product

• 5000-66-8 2-chlorophenacyl bromide 
• 72702-57-9 2-Bromo-1-(2-chlorophenyl)ethan-1-ol 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 107-10-8 propylamine 
• 62717-50-4 o-chlorostyrene oxide 

Downstream Products

• 142363-69-7 6-(2-chlorophenyl)-4-n-propylmorpholin-3-one 
• 142363-73-3 2-(2-chlorophenyl)-4-n-propylmorpholine 

Relevant articles and documents

Oxygen Isosteric Derivatives of 3-(3-Hydroxyphenyl)-N-n-propylpiperidine

Some substituted 3-phenylmorpholines (10a-e,j,k) and 3-thienylmorpholines (10f,g), isosteres of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP), were prepared and submitted to binding assays on D-2 dopaminergic and 5-HT1 and 5-HT2 serotonergic receptors, in comparison with 3-PPP and its analogue 3a,b.The results show the loss of D-2 affinity for all morpholines, while a certain activity was still observable for piperidine derivatives.Regarding the serotonergic affinity, only chloro and methoxy derivatives (10a-d) were moderately active on the 5-HT1A receptor, either when the substituent was in the C-2 or C-3 position, whereas no tested compounds showed affinity toward the 5-HT2 receptor.