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142381-30-4

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142381-30-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 142381-30-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,3,8 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 142381-30:
(8*1)+(7*4)+(6*2)+(5*3)+(4*8)+(3*1)+(2*3)+(1*0)=104
104 % 10 = 4
So 142381-30-4 is a valid CAS Registry Number.

142381-30-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Boc-Nalpha-methyl-D-tryptophan

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:142381-30-4 SDS

142381-30-4Downstream Products

142381-30-4Relevant articles and documents

Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues

Nieman, James A.,Coleman, John E.,Wallace, Debra J.,Piers, Edward,Lim, Lynette Y.,Roberge, Michel,Andersen, Raymond J.

, p. 183 - 199 (2003)

The antimitotic sponge tripeptide hemiasterlin (1) and a number of structural analogues have been synthesized and evaluated in cell-based assays for both cytotoxic and antimitotic activity in order to explore the SAR for this promising anticancer drug lead. One synthetic analogue, SPA110 (8), showed more potent in vitro cytotoxicty and antimitotic activity than the natural product hemiasterlin (1), and consequently it has been subjected to thorough preclinical evaluation and targeted for clinical evaluation. The details of the synthesis of hemiasterlin (1) and the analogues and a discussion of how their biological activities vary with their structures are presented in this paper.

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