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Usage

Uses

Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[(phenylthio)methyl]is used as a potential drug candidate for various therapeutic applications due to its unique chemical structure. Its specific biological activity and mechanism of action may vary depending on the target disease or condition.
Used in Chemical Synthesis:
2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[(phenylthio)methyl]serves as a building block for the synthesis of other organic compounds. Its unique structure allows for further chemical modifications and functionalization, enabling the development of new molecules with tailored properties and potential applications in various industries.

Upstream product

• 15018-59-4 5-bromo-1,3,6-trimethylpyrimidine-2,4(1 H,3H)-dione 
• 108-98-5 thiophenol 
• 13509-52-9 1,3,6-trimethyluracil 
• 882-33-7 diphenyldisulfane 

Relevant academic research and scientific papers

Research on antiviral agents. 5.1 lithiation of 6-methyluracil as a new and efficient entry to C(6)-substituted uracils

Synthesis of numerous C(6)-substituted uracits can be effected by lithiation of N(1), N(3)-substituted 6-methyluracils (1) and (4) with LiHMDS, followed by the reaction of the resulting lithio derivatives with carbon, sulfur, and selenium electrophiles. The unexpected migration of the N(1)-benzoyl group in the melalation-alkylation and the high stereoselectivity obtained in the reaction with substituted cyclohexanones are also reported.

PHASE TRANSFER CATALYSED OXIDATIVE ARYLTHIOLATION OF 1,3,6-TRIMETHYLURACIL AND ITS 5-BROMO DERIVATIVE

Reaction of 1,3,6-trimethyluracil and its 5-bromo derivative with arylthiole under phase transfer catalytic conditions provides C-H substitution products, 5-arylthio-1,3,6-trimethyluracils and 5-arylthio-6-arylthiomethyl-1,3-dimethyluracils.