1424192-30-2

Upstream product

• 1139-52-2 4-bromo-2,6-di-tert-butylphenol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1424192-27-7 (((2R,3R)-3-(2-(benzyloxy)ethyl)-3-methyloxiran-2-yl)methoxy)(tert-butyl)dimethylsilane 
• 118495-99-1 methylaluminium bis(4-bromo-2,6-di-tert.-butylphenoxide) 

Downstream Products

• 1424192-33-5 (S)-(2-(2-(benzyloxy)ethyl)-2-methylbut-3-enyloxy)(tert-butyl)dimethylsilane 
• 1424192-36-8 (S)-2-(2-(benzyloxy)ethyl)-2-methylbut-3-en-1-ol 
• 1424192-39-1 (2S)-2-[(2-(benzyloxy)ethyl)]-2-methylbut-3-enyl 2-diazoacetate 
• 1424192-68-6 (1S,5S,6R)-5-(2-(benzyloxy)ethyl)-5-methyl-3-oxabicyclo[4.1.0]heptan-2-one 
• 1424192-71-1 (1R,5S,6S)-5-(2-(benzyloxy)ethyl)-5-methyl-3-oxabicyclo[4.1.0]heptan-2-one 

Relevant academic research and scientific papers

Synthesis toward the lindenane-type sesquiterpenoid monomer of Chlorahololide A

An investigation toward the synthesis of the lindenane-type sesquiterpenoid monomer of Chlorahololide A using a Yamamoto rearrangement, intramolecular cyclopropanation reaction, 1,3-dipolar cyclization, and an intramolecular Heck reaction gave the pivotal intermediate 20. This gives a practical synthetic route that could generate further natural products of the Chloranthaceae family. Starting from alcohol (2), and on the basis of Yamamoto rearrangement, intramolecular cyclopropanation reaction, 1,3-dipolar cyclization, and intramolecular Heck reaction, the Lindenane-type sesquiterpenoid fragement (20) of Chlorahololide A (1) has been synthesized in a linear sequence of 21 steps and an overall yield of 1.8%. The flexible synthetic route could generate further natural products of the Chloranthaceae family. Copyright