1424279-01-5

Basic information

• Product Name: (1E,4E)-1-[4-(dimethylamino)phenyl]-5-(5-fluoropyridin-2-yl)penta-1,4-dien-3-one
• Synonyms: (1E,4E)-1-[4-(dimethylamino)phenyl]-5-(5-fluoropyridin-2-yl)penta-1,4-dien-3-one
• CAS NO: 1424279-01-5
• Molecular Weight: 296.344
• Mol File: 1424279-01-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1E,4E)-1-[4-(dimethylamino)phenyl]-5-(5-fluoropyridin-2-yl)penta-1,4-dien-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1E,4E)-1-[4-(dimethylamino)phenyl]-5-(5-fluoropyridin-2-yl)penta-1,4-dien-3-one(1424279-01-5)
• EPA Substance Registry System: (1E,4E)-1-[4-(dimethylamino)phenyl]-5-(5-fluoropyridin-2-yl)penta-1,4-dien-3-one(1424279-01-5)

Safety Data

• Hazardous Substances Data: 1424279-01-5(Hazardous Substances Data)

Upstream product

• 41404-58-4 2-bromo-5-fluoropyridine 
• 164118-85-8 (E)-1-[4-(dimethylamino)phenyl]pent-1-en-4-yn-3-ol 

Relevant articles and documents

Versatile synthesis of dissymmetric diarylideneacetones via a palladium-catalyzed coupling-isomerization reaction

As a twofold Michael system, the diarylideneacetone core is of particular interest in organic synthesis and for therapeutic applications. To overcome the drawbacks of the classical Claisen-Schmidt protocol, a new methodology for the synthesis of dissymmetric (hetero)diarylideneacetones has been developed. Conditions were optimized with a Box-Behnken design of experiment. The milder reaction conditions allow the efficient preparation of fluorinated, or heteroaromatic, dissymmetric diarylideneacetones which cannot be obtained through the classical Claisen-Schmidt protocol. Georg Thieme Verlag KG · Stuttgart · New York.