14243-60-8

Basic information

• Product Name: triethylphosphine gold bromide
• Synonyms: triethylphosphine gold bromide
• CAS NO: 14243-60-8
• Molecular Formula: C₆H₁₅AuBrP
• Molecular Weight: 0
• Mol File: 14243-60-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 126.5°C at 760 mmHg
• Flash Point: 27.2°C
• Appearance: /
• Vapor Pressure: 14.1mmHg at 25°C
• CAS DataBase Reference: triethylphosphine gold bromide(CAS DataBase Reference)
• NIST Chemistry Reference: triethylphosphine gold bromide(14243-60-8)
• EPA Substance Registry System: triethylphosphine gold bromide(14243-60-8)

Safety Data

• Hazardous Substances Data: 14243-60-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H15P.Au.3BrH/c1-4-7(5-2)6-3;;;;/h4-6H2,1-3H3;;3*1H/q;+3;;;/p-3

Upstream product

• 15529-90-5 (triethylphosphine)chlorogold(I) 
• 125023-10-1 {Au(OH₂)(P(C₂H₅)3)}⁽¹⁺⁾*NO₃^(1-)={Au(OH₂)(P(C₂H₅)3)}NO₃ 
• 7647-15-6 sodium bromide 
• 7558-02-3 potassium bromide 
• 97825-56-4 (phthalimido-⁽¹⁵⁾N)(triethylphosphine)gold(I) 
• 97825-55-3 [((C₂H₅)3P)AuBr₂(C₈H₄O₂N)] 
• 56213-25-3 tribromo(triethylphosphine)gold(III) 
• 53510-88-6 potassium phthalimide-15N 
• 50481-01-1 tetra-n-butylammonium dibromoaurate(I) 
• 554-70-1 triethylphosphine 
• 97825-49-5 (phthalimido)(triethylphosphine)gold(I) 

Downstream Products

• 66705-52-0 bis(2-diphenylphosphinomethyl)phenyldigold(I) 

Relevant articles and documents

Auranofin and its Analogues Show Potent Antimicrobial Activity against Multidrug-Resistant Pathogens: Structure–Activity Relationships

Due to the so-called “antibiotic resistance crisis” new antibacterial agents are urgently sought to treat multidrug-resistant pathogens. A group of gold- or silver-based complexes, of general formula [M(PEt3)X] (with M=Au or Ag, and X=Cl, Br or I), alongside with three complexes bearing a positive or negative charge—[Au(PEt3)2]Cl, K[Au(CN)2] and [Ag(PEt3)2]NO3—were prepared and comparatively tested with auranofin on a representative panel of pathogens including Gram-positive, Gram-negative and Candida strains. Interestingly, all the gold and silver complexes tested were active on Gram-positive strains, with the gold complexes having greater efficacy. The effects of the gold compounds were potentiated to a larger extent than silver compounds when tested in combination with a permeabilizing agent. A number of relevant structure–activity relationships emerged from the comparative analysis of the observed antibacterial profiles, shedding new light on the underlying molecular mechanisms of the action of these compounds.

Synthesis and spectroscopic characterization of (triethylphosphine)gold(I) complexes AuX(PEt3) (X = Cl, Br, CN, SCN), [AuL(PEt3)+] (L = SMe2, SC(NH2)2, H2O), and (μ-S)[Au(PEt3)]2

Neutral complexes of the type AuX(PEt3) (X = Br, CN, SCN) were prepared and characterized by infrared and Raman spectroscopy, with the major emphasis on the assignment of the gold-ligand vibrations and discerning the mode of bonding for the ambidentate ligands. The photosensitive cationic complexes [(Au(SMe2)(PEt3)]PF6 and {Au[SC(NH2)2](PEt3)}(Cl in addition to [Au(OH2)(PEt3)]NO3 and (μ-S)[(PEt3)Au]2 were also prepared and characterized by infrared and NMR spectroscopy. In both cases in which the ambidentate ligands SCN- and SC(NH2)2 were complexed with Au(I), the sulfur atom coordinates to the metal, providing evidence for a symbiotic relationship in these complexes.

Tertiary phosphine complexes of gold(I) and gold(III) with imido ligands: 1H, 31P, and 15N NMR spectroscopy, antiinflammatory activity, and X-ray crystal structure of (phthalimido)(triethylphosphine)gold(I)

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