142458-08-0

Basic information

• Product Name: 4-[(4-Methoxycarbonyl-5-methyl-3-oxo-cyclohex-1-enylamino)-methyl]-benzoic acid
• CAS NO: 142458-08-0
• Molecular Weight: 317.342
• Mol File: 142458-08-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[(4-Methoxycarbonyl-5-methyl-3-oxo-cyclohex-1-enylamino)-methyl]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-Methoxycarbonyl-5-methyl-3-oxo-cyclohex-1-enylamino)-methyl]-benzoic acid(142458-08-0)
• EPA Substance Registry System: 4-[(4-Methoxycarbonyl-5-methyl-3-oxo-cyclohex-1-enylamino)-methyl]-benzoic acid(142458-08-0)

Safety Data

• Hazardous Substances Data: 142458-08-0(Hazardous Substances Data)

Upstream product

• 56-91-7 p-aminomethylbenzoic acid 
• 39493-30-6 methyl 2-hydroxy-6-methyl-4-oxocyclohex-2-enecarboxylate 
• 625-33-2 3-penten-2-one 
• 39493-62-4 2-oxo-4-hydroxy-6-methyl-cyclohex-3-ene carboxylic acid methyl ester 

Relevant articles and documents

Anticonvulsant evaluation and mechanism of action of benzylamino enaminones

The mechanism of anticonvulsant action was evaluated for the benzylamino enaminones. The most potent enaminone in this series was the unsubstituted benzylamine analog (30; methyl 4-benzylamino-6-methyl-2-oxocyclohex-3-en-1-oate) which had an oral effective dose (ED50) in rats of 27 mg/kg against maximal electroshock seizures, and a concentration 10-fold less than this dose depressed excitatory synaptic transmission, and action potential firing in the rat brain in vitro.