142477-99-4Relevant academic research and scientific papers
AMINO ACID DERIVATIVES USEFUL AS RENIN INHIBITORS
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, (2008/06/13)
Compounds of the formula STR1 wherein A, B, X, Y, R 1, R 2, R 3, R 4 and R 5 are as set forth in the specification, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diasteromeric racemates as well as pharmaceutically acceptable salts thereof which inhibit the activity of the natural enzyme renin and are useful in the control or prevention of high blood pressure and cardiac insufficiency are described.
