1424888-75-4

Upstream product

• 193635-17-5 N-methoxy-N-methyl-3-((4-methylphenyl)sulfonamido)propanamide 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1424888-79-8 C₂₇H₃₉NO₅SSi 
• 1424888-85-6 C₂₅H₃₅NO₄SSi 
• 1424888-21-0 C₃₁H₄₁NO₄SSi 
• 1424888-17-4 C₂₅H₂₇NO₄S 
• 1424888-19-6 C₃₂H₃₃NO₄S 
• 1579268-88-4 4-(2,6-ditosyl-1,2,3,4,5,6-hexahydroazepino[4,3-b]indol-5-yl)phenol 
• 1579268-85-1 5-(4-((tert-butyldimethylsilyl)oxy)phenyl)-2,6-ditosyl-1,2,3,4,5,6-hexahydroazepino[4,3-b]indole 
• 1579268-52-2 N-(3-hydroxy-3-(1-tosyl-1H-indol-2-yl)propyl)-N-(4-hydroxybenzyl)-4-methylbenzenesulfonamide 
• 1579268-50-0 N-(4-((tert-butyldimethylsilyl)oxy)benzyl)-N-(3-hydroxy-3-(1-tosyl-1H-indol-2-yl)propyl)-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

A novel method for synthesizing 3-arylpyrrolidine and 4-arylpiperidine derivatives through an acid-promoted skeletal rearrangement

A novel method for synthesizing 3-arylpyrrolidine and 4-arylpiperidine derivatives through an acid-promoted skeletal rearrangement is described. Using trifluoroacetic acid as the acid promoter, an intramolecular ipso-Friedel-Crafts-type addition of phenols to allyl cations, formation of iminium cations through rearomatization of the spirocyclohexadienone units, and an intramolecular aza-Prins reaction, proceeded sequentially to afford 3-arylpyrrolidine and 4-arylpiperidine derivatives in good yield with high diastereoselectivity.