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Chlorpheniramine N-oxide is a metabolite of chlorpheniramine, an antihistamine medication, formed in the body during its metabolism. It possesses antihistaminic and sedative properties, making it a valuable component in the treatment of allergies and histamine-mediated conditions. Although it is considered less potent than chlorpheniramine, it contributes significantly to the overall therapeutic effects of the medication. Additionally, it serves as a research tool for studying the pharmacokinetics and metabolism of chlorpheniramine in the human body.

142494-45-9

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142494-45-9 Usage

Uses

Used in Pharmaceutical Industry:
Chlorpheniramine N-oxide is used as an active compound for its antihistaminic and sedative properties, contributing to the treatment of allergies, allergic reactions, and other histamine-mediated conditions.
Used in Research and Development:
Chlorpheniramine N-oxide is used as a research tool for studying the pharmacokinetics and metabolism of chlorpheniramine in the human body, aiding in the understanding of its therapeutic effects and potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 142494-45-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,4,9 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 142494-45:
(8*1)+(7*4)+(6*2)+(5*4)+(4*9)+(3*4)+(2*4)+(1*5)=129
129 % 10 = 9
So 142494-45-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H19ClN2O/c1-19(2,20)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m1/s1

142494-45-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine oxide

1.2 Other means of identification

Product number -
Other names Chlorpheniramine N-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:142494-45-9 SDS

142494-45-9Upstream product

142494-45-9Downstream Products

142494-45-9Relevant academic research and scientific papers

Novel chlorphenamine maleate oxidation impurity and preparation process thereof

-

Paragraph 0032-0035, (2020/05/02)

The invention provides a chlorphenamine maleate oxidation impurity, which has the structure defined in the specification. The invention also provides a preparation process of the chlorphenamine maleate oxidation impurity. According to the invention, the experiment results prove that the chlorphenamine maleate oxidation impurity generally exists in a chlorphenamine maleate finished product, and thestructure of the chlorphenamine maleate oxidation impurity is close to the structure of chlorphenamine maleate, so that the separation difficulty is relatively high; and the chlorphenamine maleate oxidation impurity is prepared by a simple process, can be used as a reference substance for quality control of chlorphenamine maleate, and has good application prospect.

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