142543-80-4Relevant articles and documents
Synthesis and evaluation of new 2',3'-dideoxynucleoside analogs as potential anti-AIDS and anti-herpes drugs
Faraj,Maillard,Lemaitre,Letellier,Frappier,Florent,Grierson,Monneret,Zerial
, p. 141 - 148 (2007/10/02)
Based on the known structure-activity relationships for the active anti-HIV, a series of 3'-deoxy-3'-N-functionalized thymidine analogs has been synthesized from thymidine. Evaluation for inhibitory activity against human immunodeficiency virus (HIV) replication in CEM cells and against herpes simplex virus in MRC-5 cells is reported.