1425720-77-9Relevant academic research and scientific papers
Reduction of 3-nitrophthalic anhydride by SnCl2 in different alcohols: A simple synthesis of alkyl 1,3-dihydro-3-oxo-2,1-benzisoxazole-4- carboxylates
Chicha, Hakima,Abbassi, Najat,Rakib, El Mostapha,Khouili, Mostafa,El Ammari, Lahcen,Spinelli, Domenico
, p. 1569 - 1571 (2013)
A new, mild and efficient process is developed for the synthesis of alkyl 1,3-dihydro-3-oxo-2,1-benzisoxazole-4-carboxylates through the reduction of 3-nitrophthalic anhydride by SnCl2 in different alcohols. The synthesis of benzisoxazoles bearing a sulfonamide functionality is also reported. The structure of sulfonamide 8d is confirmed by X-ray diffraction analysis.
