142581-46-2Relevant academic research and scientific papers
Chemistry of Mucohalic Acids, VII. - Asymmetric Synthesis of β-Lactam Derivatives by the Ketene-Imine Cycloaddition Utilizing Chiral Mucohalic Acid Derivatives
Duczek, Wolfram,Jaehnisch, Klaus,Kunath, Annamarie,Reck, Guenter,Winter, Gabriele,Schulz, Burkhard
, p. 781 - 788 (2007/10/02)
The ketene derivative 5 of the chiral pyrrolinone 4 underwent nonconcerted cycloadditions with imines leading to cis-β-lactams 6a-d with 99percent diastereoisomeric excess. rac-4 was resolved efficiently by crystallisation of diastereoisomeric a
