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14259-58-6

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14259-58-6 Usage

General Description

5'-deoxy-5'-iodouridine is a modified nucleoside that contains an iodine atom at the 5' position of the sugar ring. It is a synthetic chemical compound that is not commonly found in nature. 5'-deoxy-5'-iodouridine has been used in research as a tool to study nucleic acid structure and function, as well as in the development of new pharmaceuticals. The presence of the iodine atom can alter the chemical and physical properties of the nucleoside, potentially leading to changes in its biological activity. Studies have shown that 5'-deoxy-5'-iodouridine can be incorporated into RNA molecules and has been used as a probe to investigate the behavior of RNA in various biological processes.

Check Digit Verification of cas no

The CAS Registry Mumber 14259-58-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,5 and 9 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14259-58:
(7*1)+(6*4)+(5*2)+(4*5)+(3*9)+(2*5)+(1*8)=106
106 % 10 = 6
So 14259-58-6 is a valid CAS Registry Number.

14259-58-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,3R,4S,5S)-3,4-dihydroxy-5-(iodomethyl)oxolan-2-yl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 5'-iodo-5'-deoxy-uridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14259-58-6 SDS

14259-58-6Relevant articles and documents

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Verheyden,Moffatt

, p. 2093 (1964)

-

Halo sugar nucleosides. I. Iodination of the primary hydroxyl groups of nucleosides with methyltriphenoxyphosphonium iodide.

Verheyden,Moffatt

, p. 2319 - 2326 (1970)

-

4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO

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Page/Page column 279; 280, (2019/10/01)

Disclosed are halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections. Such viral infections can include tongaviridae, bunyaviridae, arenaviridae, coronaviridae, flaviviridae, picornaviridae, Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infections.

SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF

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Paragraph 0391, (2015/04/21)

Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such as a Picornavirus and/or Flaviviridae infection with one or more nucleosides, nucleotides and nucleotide analogs.

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