Fmoc-(Dmb)Leu-OH is a chemical compound derived from the amino acid leucine, featuring an Fmoc (9-fluorenylmethoxycarbonyl) protecting group and a Dmb (4,4'-dimethoxybenzhydryl) side chain protecting group. The Fmoc group shields the amine group of leucine, facilitating selective deprotection and coupling in peptide synthesis, while the Dmb group introduces steric hindrance and enhances the molecule's hydrophobicity. Fmoc-(Dmb)Leu-OH plays a crucial role in the development of peptide-based drug candidates and the study of structure-activity relationships in peptide design.
1425938-65-3
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Basic information
- Product Name: Fmoc-(Dmb)Leu-OH
- Synonyms: Fmoc-(Dmb)Leu-OH;FMoc-N-(2,4-diMethoxybenzyl)-Leu-OH
- CAS NO:1425938-65-3
- Molecular Formula: C30H33NO6
- Molecular Weight: 503.58612
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1425938-65-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 673.6±55.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.209±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.83±0.21(Predicted)
- CAS DataBase Reference: Fmoc-(Dmb)Leu-OH(CAS DataBase Reference)
- NIST Chemistry Reference: Fmoc-(Dmb)Leu-OH(1425938-65-3)
- EPA Substance Registry System: Fmoc-(Dmb)Leu-OH(1425938-65-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1425938-65-3(Hazardous Substances Data)
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1425938-65-3 Usage
Uses
Used in Pharmaceutical Research:Fmoc-(Dmb)Leu-OH is used as a building block for the synthesis of peptide-based drug candidates, contributing to the development of novel therapeutic agents with specific biological activities.
Used in Peptide Synthesis:
Fmoc-(Dmb)Leu-OH is used as a protected amino acid in solid-phase peptide synthesis, allowing for the stepwise assembly of peptides with controlled selectivity and protection of functional groups.
Used in Bioactive Compounds Synthesis:
Fmoc-(Dmb)Leu-OH is used as a key component in the synthesis of bioactive peptides, which have potential applications in various fields such as medicine, agriculture, and biotechnology.
Used in Structure-Activity Relationship Studies:
Fmoc-(Dmb)Leu-OH is used as a versatile compound in the investigation of structure-activity relationships in peptide design, enabling researchers to understand the impact of specific structural modifications on peptide function and activity.
Check Digit Verification of cas no
The CAS Registry Mumber 1425938-65-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,5,9,3 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.Calculate Digit Verification of CAS Registry Number 1425938-65:
(9*1)+(8*4)+(7*2)+(6*5)+(5*9)+(4*3)+(3*8)+(2*6)+(1*5)=183
183 % 10 = 3
So 1425938-65-3 is a valid CAS Registry Number.
1425938-65-3Upstream product
1425938-65-3Downstream Products
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Fmoc-(Dmb)Leu-OH
