1426055-48-2Relevant academic research and scientific papers
Palladium-catalyzed synthesis of aromatic carboxylic acids with silacarboxylic acids
Friis, Stig D.,Andersen, Thomas L.,Skrydstrup, Troels
, p. 1378 - 1381 (2013)
Aryl iodides and bromides were easily converted to their corresponding aromatic carboxylic acids via a Pd-catalyzed carbonylation reaction using silacarboxylic acids as an in situ source of carbon monoxide. The reaction conditions were compatible with a wide range of functional groups, and with the aryl iodides, the carbonylation was complete within minutes. The method was adapted to the double and selective isotope labeling of tamibarotene.
