142611-90-3

Basic information

• Product Name: Propanethioic acid, 3-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, S-phenyl ester, (R)-
• CAS NO: 142611-90-3
• Molecular Formula: C15H21NO4S
• Molecular Weight: 311.402
• Mol File: 142611-90-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanethioic acid, 3-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, S-phenyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanethioic acid, 3-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, S-phenyl ester, (R)-(142611-90-3)
• EPA Substance Registry System: Propanethioic acid, 3-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, S-phenyl ester, (R)-(142611-90-3)

Safety Data

• Hazardous Substances Data: 142611-90-3(Hazardous Substances Data)

Upstream product

• 79-83-4 pantothenic acid 
• 108-98-5 thiophenol 
• 142611-89-0 Trifluoro-acetic acid (R)-2,2-dimethyl-1-(2-phenylsulfanylcarbonyl-ethylcarbamoyl)-3-(2,2,2-trifluoro-acetoxy)-propyl ester 

Downstream Products

• 1096157-33-3 N-(4-trifluoromethoxy-benzyl) pantothenamide 
• 1096156-76-1 N-cyclohexylmethyl pantothenamide 
• 874304-28-6 N-(4-methoxy-benzyl) pantothenamide 
• 874304-22-0 N-phenethyl pantothenamide 
• 1096156-70-5 N-cyclohexyl pantothenamide 
• 1096157-36-6 N-(4-trifluoromethyl-benzyl) pantothenamide 
• 1096157-25-3 N-(3-methoxy-benzyl) pantothenamide 
• 874304-25-3 N-(3,4,5-trimethoxy-benzyl) pantothenamide 
• 1096157-39-9 N-(3-trifluoromethyl-benzyl) pantothenamide 
• 142611-92-5 C₂₁H₃₈NO₇PSSi₂ 
• 142611-93-6 phenyl 4'-phosphothiopantothenate 
• 142611-91-4 3-[(R)-4-(Dimethoxy-phosphoryloxy)-2-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid S-phenyl ester 

Relevant articles and documents

Development of a method for the parallel synthesis and purification of N-substituted pantothenamides, known inhibitors of coenzyme A biosynthesis and utilization

N-Substituted pantothenamides are a class of pantothenic acid analogues which have been shown to act as inhibitors of coenzyme A biosynthesis and utilization, especially by blocking fatty acid metabolism through formation of inactive acyl carrier proteins. To fully explore the chemical diversity and inhibitory potential of these analogues we have developed a simple method for the parallel synthesis and purification of any number of pantothenamides from a single precursor, and subsequently evaluated a small library of these compounds as inhibitors of bacterial growth to demonstrate the potential and utility of the method.

Combined chemical and enzymatic synthesis of coenzyme a analogs

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