142613-52-3Relevant academic research and scientific papers
Amidate Prodrugs of O-2-Alkylated Pyrimidine Acyclic Nucleosides Display Potent Anti-Herpesvirus Activity
Luo, Min,Groaz, Elisabetta,Snoeck, Robert,Andrei, Graciela,Herdewijn, Piet
supporting information, p. 1410 - 1415 (2020/07/14)
Three series of amidate prodrugs of O-2-alkylated acyclic nucleosides of the 3-fluoro-2-(phosphonomethoxy)propyl (FPMP), cyclic 3-hydroxy-2-(phosphonomethoxypropyl) (cHPMP), and 2-(phosphonomethoxypropyl) (PMP)-type featuring cytosine and 5-fluorocytosine
Synthesis and antiviral activity of methyl derivatives of 9-[2- (phosphonomethoxy)ethyl]guanine
Yu,Bronson,Yang,Patick,Alam,Brankovan,Datema,Hitchcock,Martin
, p. 2958 - 2969 (2007/10/02)
A number of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG, 1) have been synthesized and tested in vitro for anti-herpes and anti- human immunodeficiency virus (HIV) activity. Among these analogues, (R)-2'- methyl-PMEG [(R)-3] and 2',2'-
