1426142-41-7

Upstream product

• 96253-10-0 1-[2,3-epoxy-5-O-(triphenylmethyl)-β-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione 
• 1426142-28-0 1-(2-azido-2-deoxy-5-O-(triphenylmethyl)-β-D-xylofuranosyl)pyrimidine-2,4(1H,3H)-dione 
• 1426142-40-6 1-[2-azido-2-deoxy-3-O-(prop-2-yn-1-yl)-5-O-(triphenylmethyl)-β-D-xylofuranosyl]pyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 1426142-43-9 4-amino-1-{(5aR,6R,8R,8aR)-5a,6,8,8a-tetrahydro-6-[(triphenylmethoxy)methyl]-4H-furo[3,4-b][1,2,3]triazolo[1,5-d][1,4]oxazin-8-yl}pyrimidin-2(1H)-one 

Relevant academic research and scientific papers

Synthesis and Anti-HIV activity of triazolo-fused 2′,3′-cyclic nucleoside analogs prepared by an intramolecular huisgen 1,3-dipolar cycloaddition

Triazolo-fused 2′,3′-cyclic nucleoside analogs were synthesized by an intramolecular 1,3-dipolar cycloaddition of nucleoside-derived azido alkynes in a regio- and stereospecific manner. The uracil base in these target compounds was successfully transformed to the corresponding cytosine. The synthesized compounds were examined in a MAGI assay for their anti-HIV activities, and in a H9 T lymphocytes assay for their cell toxicities. Copyright