1426146-04-4Relevant articles and documents
Syntheses of the C1-C14 and C15-C25 fragments of amphidinolide C
Wu, Dimao,Forsyth, Craig J.
supporting information, p. 1178 - 1181 (2013/04/24)
Divergent syntheses of the C1-C14 and C15-C25 fragments of amphidinolide C have been achieved. The synthesis of the C15-C25 fragment featured cobalt-catalyzed modified Mukaiyama aerobic alkenol cyclization and sulfur-directed regiocontrolled Wacker oxidation of an internal alkene. The C1-C14 fragment was established by alkenyllithium addition to an aldehyde followed by a challenging olefination of a highly inert C9 ketone.