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N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)quinoline-7-sulfonamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1426232-01-0 Structure
  • Basic information

    1. Product Name: N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)quinoline-7-sulfonamide
    2. Synonyms: N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)quinoline-7-sulfonamide
    3. CAS NO:1426232-01-0
    4. Molecular Formula:
    5. Molecular Weight: 493.457
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1426232-01-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)quinoline-7-sulfonamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)quinoline-7-sulfonamide(1426232-01-0)
    11. EPA Substance Registry System: N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)quinoline-7-sulfonamide(1426232-01-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1426232-01-0(Hazardous Substances Data)

1426232-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1426232-01-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,6,2,3 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1426232-01:
(9*1)+(8*4)+(7*2)+(6*6)+(5*2)+(4*3)+(3*2)+(2*0)+(1*1)=120
120 % 10 = 0
So 1426232-01-0 is a valid CAS Registry Number.

1426232-01-0Downstream Products

1426232-01-0Relevant articles and documents

Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT 1A/5-HT2A/5-HT7 and dopamine D 2/D3 receptors

Zajdel, Pawel,Marciniec, Krzysztof,Maslankiewicz, Andrzej,Grychowska, Katarzyna,Satala, Grzegorz,Duszynska, Beata,Lenda, Tomasz,Siwek, Agata,Nowak, Gabriel,Partyka, Anna,Wrobel, Dagmara,Jastrzebska-Wiesek, Magdalena,Bojarski, Andrzej J.,Wesolowska, Anna,Pawlowski, MacIej

, p. 42 - 50 (2013/04/23)

A series of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole was synthesized to explore the influence of two structural features-replacement of ether/amide moiety with sulfonamide one, and localization of a sulfonamide group in the azine moiety. In contrast to aripiprazole, compound 33 (N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl) quinoline-7-sulfonamide) and 39 (N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl) butyl)isoquinoline-3-sulfonamide) displaying multireceptor 5-HT 1A/5-HT2A/5-HT7/D2/D3 profile, and behaving as 5-HT1A agonists, D2 partial agonists, and 5-HT2A/5-HT7 antagonists, produced significant antidepressant activity in FST in mice. On the other hand, their 4-isoquinolinyl analog 40 (N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl) isoquinoline-4-sulfonamide), with similar receptor binding and functional profile, additionally displayed remarkable antipsychotic properties in the MK-801-induced hyperlocomotor activity in mice.

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