1426249-32-2Relevant academic research and scientific papers
Copper-Mediated Synthesis of Aryl α-Keto Amides from Epoxide Derivatives
Cui, Yunjian,Dong, Yi,Liu, Fenghua,Xu, Heng
supporting information, p. 1011 - 1014 (2020/06/10)
A novel Cu II -mediated synthesis of aryl α-keto amides from epoxide derivatives is reported. This transformation was conducted by using O 2 as a green oxidant that meets the requirements of sustainable chemistry.
TBAI-catalyzed synthesis of α-ketoamides via sp3 C-H radical/radical cross-coupling and domino aerobic oxidation
Fan, Weizheng,Shi, Dongyang,Feng, Bainian
, p. 4638 - 4641 (2015/07/02)
A TBAI-catalyzed one-pot synthesis of α-ketoamides via sp3 C-H radical/radical cross-coupling and domino aerobic oxidation was developed. This synthesis is suitable for abroad range of substrates. The control experiments suggested a possible oxidative coupling mechanism.
Synthesis of α-ketoamides from Aryl methyl ketones and N, N -dimethylformamide via copper-catalyzed aerobic oxidative coupling
Zhou, Mingxin,Song, Qiuling
, p. 1853 - 1858 (2014/07/22)
A copper-catalyzed aerobic oxidative coupling of aryl methyl ketones with N,N-dimethylformamide was developed, which afforded α-ketoamides by a sequence of dioxygen activation, C-H bond functionalization, and amide formation with N,N-dimethylformamide as
Copper-catalyzed oxidative condensation of α-oxocarboxylic acids with formamides: Synthesis of α-ketoamides
Wang, Hua,Guo, Li-Na,Duan, Xin-Hua
supporting information, p. 4573 - 4576 (2013/07/26)
A copper-catalyzed coupling of α-oxocarboxylic acids with formamides is reported. This simple method provides a practical approach toward the synthesis of α-ketoamides with a variety of functional groups. Mechanistic studies have shown that the reaction proceeded via a radical process and 13C-labeled experiments proved that the amide carbon in the products comes from the corresponding carboxylic acid, not from the DMF. is
Cu(ii)-catalyzed decarboxylative acylation of acyl C-H of formamides with α-oxocarboxylic acids leading to α-ketoamides
Li, Dengke,Wang, Min,Liu, Jie,Zhao, Qiong,Wang, Lei
supporting information, p. 3640 - 3642 (2013/05/21)
CuBr2-catalyzed decarboxylative acylation of the acyl C-H of N-monosubstituted and N,N-disubstituted formamides with α-oxocarboxylic acids leading to α-ketoamides was developed, which generated the corresponding products in good yields. The Royal Society of Chemistry 2013.
Direct use of formamides as amino group sources via C-N bond cleavage: A catalytic oxidative synthesis of α-ketoamides from acetophenones and formamides under metal-free conditions
Zhao, Qiong,Miao, Tao,Zhang, Xiaobin,Zhou, Wei,Wang, Lei
, p. 1867 - 1873 (2013/04/10)
An efficient and direct use of formamides as amino group sources for the synthesis of α-ketoamides was developed under metal-free conditions. The reaction was based on the oxidative coupling of acetophenones with formamides and generated the desired products in good yields in the presence of t-BuOOH/I2/PhCO2H.
