1426256-92-9Relevant articles and documents
Efficient and practical synthesis of enantioenriched 2,3-dihydropyrroles through gold-catalyzed anti-Markovnikov hydroamination of chiral homopropargyl sulfonamides
Yu, Yong-Fei,Shu, Chao,Zhou, Bo,Li, Jian-Qiao,Zhou, Jin-Mei,Ye, Long-Wu
, p. 2126 - 2129 (2015/02/05)
A direct gold-catalyzed 5-endo-dig cycloisomerization of chiral homopropargyl sulfonamides has been developed. A range of enantioenriched 2,3-dihydropyrroles are readily accessed by utilizing this approach. Importantly, this gold-catalyzed cycloisomerization reaction proceeds through an anti-Markovnikov addition by using a catalytic base as the additive, which completely suppresses the undesired dimerization. This journal is