1426257-83-1Relevant academic research and scientific papers
Effect of ester on rhodium-catalyzed intermolecular [5+2] cycloaddition of 3-acyloxy-1,4-enynes and alkynes
Schienebeck, Casi M.,Robichaux, Patrick J.,Li, Xiaoxun,Chen, Lianqing,Tang, Weiping
supporting information, p. 2616 - 2618 (2013/04/23)
We systematically examined the effect of different esters on the rhodium-catalyzed intermolecular [5+2] cycloaddition of 3-acyloxy-1,4-enynes and alkynes with a concomitant 1,2-acyloxy migration. Significant rate acceleration was observed for benzoate substrates bearing an electron-donating substituent. The cycloaddition can now be conducted under much more practical conditions for most terminal alkynes. The Royal Society of Chemistry 2013.
