1426324-49-3Relevant academic research and scientific papers
Synthesis of the C1-C10 Fragment of Madeirolide A
Hwang, Sunghyun,Baek, Inhwan,Lee, Chulbom
, p. 2154 - 2157 (2016)
The synthesis of a fully elaborated C1-C10 fragment of madeirolide A has been achieved via a strategy based on a series of stereospecific processes. The concise synthetic route also features an iridium-catalyzed visible light induced radical cyclization for construction of the THP ring and a palladium-catalyzed glycosylation for formation of the α-cineruloside linkage.
Synthesis of the C1-C11 western fragment of madeirolide A
Paterson, Ian,Haslett, Gregory W.
, p. 1338 - 1341 (2013/05/09)
The stereocontrolled synthesis of a fully elaborated C1-11 subunit of madeirolide A is described, utilizing an asymmetric boron aldol reaction and a cis-selective hetero-Michael cyclization to form the tetrahydropyran ring, followed by efficient formation of the required C5 α-glycoside.
