1426327-08-3Relevant academic research and scientific papers
Soluble tag-assisted peptide head-to-tail cyclization: Total synthesis of mahafacyclin B
Fujita, Yuko,Fujita, Shuji,Okada, Yohei,Chiba, Kazuhiro
, p. 1155 - 1157 (2013/05/09)
A soluble tag-assisted liquid-phase method was successfully applied to peptide head-to-tail cyclization, leading to the total synthesis of antimalarial cyclic heptapeptide, mahafacyclin B (1). The cyclization was carried out in the liquid phase with the tag remaining, which allowed rapid reaction workup and product isolation.
