1426396-29-3Relevant academic research and scientific papers
A benzothiazole-based near-infrared fluorescent probe for sensing SO2 derivatives and viscosity in HeLa cells
Li, Yibing,Zhu, Yilin,Cai, Xuzi,Guo, Jimin,Yao, Cuiping,Pan, Qiling,Wang, Xuefeng,Wang, Kang-Nan
, (2021)
The unbalanced metabolism of sulfur dioxide can cause various diseases, such as neurological disorders and lung cancer. Until now, some researches revealed that the normal function of lysosomes would be disrupted by its abnormal viscosity. As a signal molecule, sulfur dioxide (SO2) plays an important role in lysosome metabolism. However, the connection of metabolism between the SO2 and viscosity in lysosomes is still unknown. Herein, we developed a benzothiazole-based near-infrared (NIR) fluorescent probe (Triph-SZ), which can monitor the SO2 derivatives and respond to the change of viscosity in lysosomes through two-photon imaging. Triph-SZ present high sensitivity and selectivity fluorescence response with the addition of SO2 derivatives based on the nucleophilic addition, and it also exhibits a sensitive fluorescence enhancement to environmental viscosity, which allows Triph-SZ to be employed to monitor the level of HSO3? and viscosity changes in lysosomes by the two-photon fluorescence lifetime imaging microscopy.
Highly reactive (<1 min) ratiometric probe for selective 'naked-eye' detection of cyanide in aqueous media
Goswami, Shyamaprosad,Manna, Abhishek,Paul, Sima,Aich, Krishnendu,Das, Avijit Kumar,Chakraborty, Shampa
, p. 1785 - 1789 (2013/05/09)
We have designed and synthesized a triphenyl aminebenzothiazole coupled receptor (TBH) that exhibits a selective, sensitive, colorimetric, and ratiometric rapid response toward cyanide anion in aqueous media. The sensing event is explained by spectroscopy along with DFT calculation and CV diagram. Sensor displays a very fast response (- and AcO- in aqueous media.
