1426400-93-2Relevant articles and documents
Huenlich base: (Re)discovery, synthesis, and structure elucidation after a century
Rigol, Stephan,Beyer, Lothar,Hennig, Lothar,Sieler, Joachim,Giannis, Athanassios
, p. 1418 - 1420 (2013)
After almost 100 years, the structure of the product of the reaction between 2,4-diaminotoluene and formaldehyde was elucidated: derivative 3, which we call the Huenlich base, was synthesized on a multigram scale and its enantiomers were easily separated in preparative amounts. Furthermore, transformation of the NH2 groups to the corresponding bis-iodides and bis-azides is presented. The latter was also used for desymmetrization by click chemistry.
