1426413-76-4Relevant academic research and scientific papers
Magnetically recyclable γ-Fe2O3-HAP nanoparticles for the cycloaddition reaction of alkynes, halides and azides in aqueous media
Kale, Sandip R.,Kahandal, Sandeep S.,Gawande, Manoj B.,Jayaram, Radha V.
, p. 8184 - 8192 (2013)
A simple and novel γ-Fe2O3 supported on hydroxyapatite (HAP) heterogeneous catalytic system is described that is useful in the synthesis of disubstituted 1,2,3-triazoles from terminal alkynes and in situ generated organic azide in aqueous media; this green methodology emerges as this new catalyst for the one-pot synthesis of 1,2,3-triazoles can be used in water without the addition of any reagent/base. The catalyst can be successfully recycled five times without significant loss of activity. It is important to note that 100% regioselectivity was observed for the cycloaddition reaction.
