1426414-50-7

Basic information

• Product Name: (S)-tert-butyl 3-(1-hydroxy-1-phenylethyl)-1H-indole-1-carboxylate
• Synonyms: (S)-tert-butyl 3-(1-hydroxy-1-phenylethyl)-1H-indole-1-carboxylate
• CAS NO: 1426414-50-7
• Molecular Weight: 337.419
• Mol File: 1426414-50-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 3-(1-hydroxy-1-phenylethyl)-1H-indole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 3-(1-hydroxy-1-phenylethyl)-1H-indole-1-carboxylate(1426414-50-7)
• EPA Substance Registry System: (S)-tert-butyl 3-(1-hydroxy-1-phenylethyl)-1H-indole-1-carboxylate(1426414-50-7)

Safety Data

• Hazardous Substances Data: 1426414-50-7(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 26340-47-6 3-Iodo-1H-indole 
• 98-85-1 1-Phenylethanol 
• 1445-91-6 (S)-1-phenylethanol 
• 942070-45-3 tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate 
• 133038-74-1 (S)-(-)-1-phenylethyl N,N-diisopropylcarbamate 
• 192189-07-4 tert-butyl 3-iodo-1H-indol-1-carboxylate 

Relevant articles and documents

Asymmetric synthesis of 1-heteroaryl-1-arylalkyl tertiary alcohols and 1-pyridyl-1-arylethanes by lithiation-borylation methodology

The synthesis of highly enantioenriched α-heterocyclic tertiary alcohols has been achieved via lithiation-borylation of a configurationally stable lithiated carbamate and heterocyclic pinacol boronic esters followed by oxidation. Protodeboronation of the α-heterocyclic tertiary boronic esters using TBAF·3H2O or CsF gave highly enantioenriched 1-pyridyl-1-arylethanes in high er.