1426427-37-3

Basic information

• Product Name: C₂₈H₂₀O₇
• Synonyms: C₂₈H₂₀O₇
• CAS NO: 1426427-37-3
• Molecular Weight: 468.463
• Mol File: 1426427-37-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₀O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₀O₇(1426427-37-3)
• EPA Substance Registry System: C₂₈H₂₀O₇(1426427-37-3)

Safety Data

• Hazardous Substances Data: 1426427-37-3(Hazardous Substances Data)

Upstream product

• 298-81-7 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one 
• 1930-54-7 4-bromo-9-methoxy-7H-furo[3,2-g]chromen-7-one 
• 1426427-33-9 C₁₅H₁₀O₆ 
• 13826-35-2 3-Phenoxybenzyl alcohol 

Relevant articles and documents

Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives

A series of 5- and 8-methoxypsoralen (MOP) analogs, suitable for structure-antioxidative/anti-inflammatory activity relationship studies, were synthesized using as key-reactions the selective monobromination of MOPs with N-bromosaccharin and either a Heck reaction or a Suzuki coupling or a Suzuki coupling followed by a Wittig reaction to install side-chains of the acrylate- or benzoate- or cinnamate-type, respectively. The 8-MOP analogs 19 and 24, incorporating at position 5 of the psoralen nucleus a butyl acrylate or a tert-butyl cinnamate moiety, were the most powerful inhibitors of soybean LOX and inhibited effectively lipid peroxidation. Analog 19 was a more potent anti-inflammatory agent than the reference compound indomethacin and of comparable cytocompatibility to 8-MOP whereas analog 24 was a weaker inhibitor of inflammation than indomethacin and significantly more cytotoxic than 8-MOP. The results of the biological tests are discussed in terms of structural characteristics.