1426439-03-3Relevant academic research and scientific papers
Polystyrene-supported p-toluenesulfonic acid: A new, highly efficient, and recyclable catalyst for the synthesis of hydropyridine derivatives under solvent-free conditions
Reddy, Mudumala Veeranarayana,Jeong, Yeon Tae
, p. 2985 - 2991 (2012)
A new environmentally benign method for the preparation of hydropyridine derivatives has been developed by a simple one-pot condensation reaction of dimidine, active methylene compounds with aldehydes, and ammonium acetate in the presence of polystyrene-supported p-toluenesulfonic acid as a highly active and reusable heterogeneous acid catalyst under solvent-free conditions at 60°C. This new protocol has the advantages of easy availability, stability, reusability, and eco-friendliness of the catalyst, high to excellent yields, simple and easy experimental workup procedure. Georg Thieme Verlag KG · Stuttgart · New York.
