1426447-41-7

Upstream product

• 1426533-79-0 (3S,4S,6S,7S)-3,5,7-trimethylnona-1,8-diene-4,6-diol 
• 1426447-34-8 (3R,4S)-4-((2R,3S,4S)-3-((4-methoxybenzyl)oxy)-4-methylhex-5-en-2-yl)-3-methyloxetan-2-one 
• 1426447-33-7 (2R,3R,4S,5S,6S)-3-hydroxy-5-((4-methoxybenzyl)oxy)-2,4,6-trimethyloct-7-enoic acid 
• 1426447-40-6 (R)-2-((2R,3R,4R,5R,6S)-6-(iodomethyl)-4-((4-methoxybenzyl)oxy)-3,5-dimethyltetrahydro-2H-pyran-2-yl)propanoic acid 
• 1426447-32-6 (2S,3R,4R,5R,6S)-2-((S)-but-3-en-2-yl)-6-(iodomethyl)-4-((4-methoxybenzyl)oxy)-3,5-dimethyltetrahydro-2H-pyran 
• 1426447-39-3 (2S,3R,4R,5R,6S)-2-((S)-but-3-en-2-yl)-6-(iodomethyl)-3,5-dimethyltetrahydro-2H-pyran-4-ol 

Downstream Products

• 1426447-42-8 (R)-2-((2S,4S,5R,6S)-6-((S)-but-3-en-2-yl)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)propanoic acid 
• 15797-36-1 (3R,4S,5R,6S,7S,9R,11R,12S,13R,14R)-14-ethyl-4,6,12-trihydroxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 

Relevant academic research and scientific papers

Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation

The 14-membered macrolide 6-deoxyerythronolide B is prepared in 14 steps (longest linear sequence) and 20 total steps. Two different methods for alcohol CH-crotylation via transfer hydrogenation are deployed for the first time in target-oriented synthesis