1426547-55-8

Basic information

• Product Name: 5-chloro-2',6'-bis(methoxymethoxy)biphenyl-2-carboxaldehyde
• Synonyms: 5-chloro-2',6'-bis(methoxymethoxy)biphenyl-2-carboxaldehyde
• CAS NO: 1426547-55-8
• Molecular Weight: 336.772
• Mol File: 1426547-55-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-2',6'-bis(methoxymethoxy)biphenyl-2-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2',6'-bis(methoxymethoxy)biphenyl-2-carboxaldehyde(1426547-55-8)
• EPA Substance Registry System: 5-chloro-2',6'-bis(methoxymethoxy)biphenyl-2-carboxaldehyde(1426547-55-8)

Safety Data

• Hazardous Substances Data: 1426547-55-8(Hazardous Substances Data)

Upstream product

• 2420-26-0 4-chlorosalicylaldehyde 

Relevant articles and documents

Enantioselective synthesis of multisubstituted biaryl skeleton by chiral phosphoric acid catalyzed desymmetrization/kinetic resolution sequence

Described herein is the enantioselective synthesis of multisubstituted biaryl derivatives by chiral phosphoric acid catalyzed asymmetric bromination. Two asymmetric reactions (desymmetrization and kinetic resolution) proceeded successively to afford chiral biaryls in excellent enantioselectivities (up to 99% ee). Both experimental and computational studies suggested that this excellent selectivity could be achieved via a highly organized hydrogen bond network among a substrate, a catalyst (chiral phosphoric acid), and a brominating reagent (N-bromophthalimide).