1426563-34-9

Upstream product

• 108-24-7 acetic anhydride 
• 188802-60-0 C₁₀H₁₇NO₇ 
• 73960-72-2 methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate 

Downstream Products

• 1426563-33-8 methyl 4-acetamido-7,8,9-tri-O-acetyl-2,6-anhydro-5-(benzyloxyacetamido)-4,3,5-trideoxy-D-glycero-D-talonon-2-enonate 

Relevant academic research and scientific papers

Simple and rapid procedures for the synthesis of 5-acylated 4β-acylamido-and 4β-acetoxyneuraminic acid glycals

Two simple and rapid procedures affording 4β-acylamido-and 4β-acetoxyneuraminic acid glycals acylated or perfluoroacylated at the 5-amino group are reported. The first protocol avoids the formation of oxazolines to synthesize the 4β-acetamido glycals through the Ritter reaction. The second passes through the oxazoline derivative to prepare 4β-acetoxyneuraminic acid glycals. Both protocols start from peracetylated methyl neuraminate, acylated at the amino group with a normal, a glycolyl, or a perfluoroacyl group, or with the corresponding peracetylated glycal methyl esters (of the DANA or FANA series).