1426580-39-3Relevant academic research and scientific papers
Synthesis, X-ray diffraction study, and cytotoxicity of a cationic p-cymene ruthenium chloro complex containing a chelating semicarbazone ligand
Zhou, Quan,Li, Peiyuan,Lu, Rumei,Qian, Quanquan,Lei, Xiaolin,Xiao, Qi,Huang, Shan,Liu, Lifeng,Huang, Chusheng,Su, Wei
, p. 943 - 946 (2013)
An organometallic salt composed of a new cationic p-cymene ruthenium chloro complex containing a chelating benzaldehyde semicarbazone ligand and of the known anionic p-cymene ruthenium trichloro complex, [(η6-p- cymene)Ru(bzsc)Cl]+[(η6-p-cymene)RuCl 3]- (1) (bzsc = benzaldehyde semicarbazone) was synthesized and further characterized by IR, 1H NMR, and UV/Vis spectroscopy HR-ESI mass spectrometry, and elemental analysis. The single-crystal structure of 1 was also determined. The in vitro anticancer activities of the complex was evaluated against three human cancer cell lines (SGC-7901, BEL-7404 and CNE-1), and the IC50 values were 20.7, 71.1 and 42.6 μM, respectively. Copyright
