1426654-57-0

Basic information

• Product Name: (1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)(phenyl)methanone
• Synonyms: (1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)(phenyl)methanone
• CAS NO: 1426654-57-0
• Molecular Weight: 236.273
• Mol File: 1426654-57-0.mol

Chemical Properties

• CAS DataBase Reference: (1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)(phenyl)methanone(1426654-57-0)
• EPA Substance Registry System: (1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)(phenyl)methanone(1426654-57-0)

Safety Data

• Hazardous Substances Data: 1426654-57-0(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 27257-15-4 1-methyl-1H-pyrrolo[2,3-b]pyridine 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 98-80-6 phenylboronic acid 
• 271-63-6 7-Azaindole 
• 611-73-4 Benzoylformic acid 
• 100-47-0 benzonitrile 

Relevant articles and documents

Synthesis of indol-3-yl aryl ketones through visible-light-mediated carbonylation

A visible-light-catalyzed synthesis of indol-3-yl aryl ketones from aryldiazonium salts, CO and indoles at room temperature was developed. This process provides a useful method for the preparation of diverse indol-3-yl aryl ketones from readily accessible reactants under base-free, acid-free and transition-metal-free conditions.

Acylation of indoles via photoredox catalysis: A route to 3-acylindoles

A visible-light-induced synthesis of 3-acylindoles from simple indoles and α-oxo acids at room temperature has been discovered. The reaction tolerates a wide range of functional groups and gives a variety of valuable 3-acylindoles in moderate to high yields under mild conditions.

Palladium-catalyzed carbonylation of indoles for synthesis of indol-3-yl aryl ketones

A novel palladium-catalyzed carbonylation of indoles with CO and aromatic boronic acids for the synthesis of indol-3-yl aryl ketones was developed. The reaction tolerates a wide range of functional groups and gives a variety of valuable indol-3-yl aryl ketones in high yields under mild conditions. (Chemical Presented).

Copper-promoted decarboxylative direct C3-acylation of N-substituted indoles with α-oxocarboxylic acids

A novel and efficient Cu-promoted decarboxylative direct C3-acylation of N-substituted indoles with α-oxocarboxylic acids for the synthesis of 3-acylindoles was developed. The Royal Society of Chemistry.

Facile access to 3-acylindoles through palladium-catalyzed addition of indoles to nitriles: The one-pot synthesis of indenoindolones

A palladium-catalyzed addition of indoles to nitriles, leading to 3-acylindoles, was reported, and the scope of nitriles was investigated. The strategy described provides a more efficient and atom-economical alternative to indenoindolones. It was found that alkenyl, carbonyl, halogen, methoxy, and nitro groups on aryl nitriles, which could offer opportunities for further synthetic transformations, are all compatible with the conditions. N-unprotected indoles with electron-rich groups show excellent reactivity towards this addition reaction. Under the optimized conditions, an array of indenoindolones are obtained in synthetic useful yields from readily available indoles and nitriles in one pot. The results also show that both the electron-poor and electron-rich substituents could be introduced to indoles and nitriles and that the halogen atoms were compatible under the current conditions.