1426677-86-2

Upstream product

• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 1426678-03-6 C₂₂H₂₀ClNO₄S 
• 135484-67-2 N-(5-chloro-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide 
• 37585-16-3 (2-amino-4-chlorophenyl)methanol 

Downstream Products

• 1426678-19-4 (R)-7-chloro-3-hydroxy-3-phenyl-1-tosyl-2,3-dihydroquinolin-4(1H)-one 

Relevant academic research and scientific papers

N-heterocyclic carbene-catalyzed enantioselective intramolecular N-tethered aldehyde-ketone benzoin reactions

The N-heterocyclic carbene-catalyzed enantioselective intramolecular benzoin reaction of N-tethered substrates was realized. With 15 mol % of d-camphor-derived triazolium salt E and 10 mol % of NaOAc, the aldehyde-ketone cross benzoin reactions of various substituted N-tethered substrates proceeded smoothly to afford dihydroquinolinone derivatives with a quaternary carbon stereocenter in moderate to good yields and excellent ee.