1426679-86-8

Basic information

• Product Name: 5-((tert-butyldimethylsilyl)oxy)-5-(4-methoxyphenyl)pentanal
• Synonyms: 5-((tert-butyldimethylsilyl)oxy)-5-(4-methoxyphenyl)pentanal
• CAS NO: 1426679-86-8
• Molecular Weight: 322.52
• Mol File: 1426679-86-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-((tert-butyldimethylsilyl)oxy)-5-(4-methoxyphenyl)pentanal(CAS DataBase Reference)
• NIST Chemistry Reference: 5-((tert-butyldimethylsilyl)oxy)-5-(4-methoxyphenyl)pentanal(1426679-86-8)
• EPA Substance Registry System: 5-((tert-butyldimethylsilyl)oxy)-5-(4-methoxyphenyl)pentanal(1426679-86-8)

Safety Data

• Hazardous Substances Data: 1426679-86-8(Hazardous Substances Data)

Upstream product

• 4609-10-3 5-(4-methoxyphenyl)-5-oxopentanoic acid 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 108-55-4 glutaric anhydride, 
• 1426679-85-7 (R)-ethyl 5-(tert-butyldimethylsilyloxy)-5-(4-methoxyphenyl)pentanoate 
• 1426679-84-6 (R)-ethyl 5-hydroxy-5-(4-methoxyphenyl)pentanoate 
• 25305-58-2 ethyl 5-(4-methoxyphenyl)-5-oxopentanoate 

Downstream Products

• 1426679-87-9 (R)-tert-butyl(1-(4-methoxyphenyl)hex-5-enyloxy)dimethylsilane 
• 1172594-99-8 (R) 1-(4-methoxyphenyl)-5-hexen-1-ol 
• 1426679-89-1 1-(4-(tert-butyldimethylsilyloxy)phenyl)-2-((2R,6R)-6-(4-methoxyphenyl)tetrahydro-2H-pyran-2-yl)ethanone 
• 1426679-88-0 1-(4-(tert-butyldimethylsilyloxy)phenyl)-2-((2S,6R)-6-(4-methoxyphenyl)tetrahydro-2H-pyran-2-yl)ethanone 
• 1451998-77-8 1-(4-hydroxyphenyl)-2-((2S,6R)-6-(4-methoxyphenyl)tetrahydro-2H-pyran-2-yl)ethanone 

Relevant articles and documents

Ru-catalyzed asymmetric hydrogenation of δ-keto Weinreb amides: Enantioselective synthesis of (+)-Centrolobine

An efficient asymmetric hydrogenation of δ-keto Weinreb amides catalyzed by a Ru-Xyl-SunPhos-Daipen bifunctional catalyst has been achieved. This method afforded a series of enantio-enriched δ-hydroxy Weinreb amides in good yields (up to 93%) and enantioselectivities (up to 99%). This protocol was successfully applied to the synthesis of the key intermediate of (+)-Centrolobine.