1426681-72-2Relevant academic research and scientific papers
Design, synthesis and aromatase inhibitory activities of novel indole-imidazole derivatives
Wang, Rui,Shi, Hong-Fan,Zhao, Jing-Feng,He, Yan-Ping,Zhang, Hong-Bin,Liu, Jian-Ping
supporting information, p. 1760 - 1762 (2013/04/10)
A series of novel indole-imidazole derivatives have been prepared and evaluated in vitro on the aromatase inhibitory activities. The results suggested that proton or a small electron-withdrawing group at para-position of the phenyl ring would enhance the inhibitory activities and any bulky group should be avoided in order to keep a relative small volume for this kind of molecules.
